A recent report by Wang et al. (2019) of the role of the miR-1205-EGLN3 axis in PCa suggests that there is somatic DNA amplification at the locus for PVT1-encoded miRs-1204-1208 and that this is correlated with miR-1205 overexpression in PC-3 cells. This evidence concerns the gene PVT1 and posterior cortical atrophy.