In line with this, an isocaloric 20% kcal fat diet consisting of n-6 and n-3 FAs in a ratio of 1:1 (n-3 diet) reduced tumor growth rates, tumor volumes, and serum PSA levels in LAPC-4 xenografts with respect to n-6 FAs-based diet (n-6 diet). Here, PROS1 is linked to neoplasm.