In osteosarcoma, circXPO1 sponges multiple microRNAs, including miR-23a-3p, miR-23b-3p, miR-23c, and miR-130a-5p, to upregulate XPO1 expression (15), which suggests that circXPO1 facilitates cancer progression by acting as a competing endogenous RNA. This evidence concerns the gene XPO1 and cancer.