CXCL12 and ovarian cancer: Meanwhile, the chemokine landscape of ovarian cancer was found to be quite heterogeneous, because of different functions of known lymphocyte-recruiting chemokines in TME, such as CCL2, CXCL9, CXCL10, CXCL12, and CXCL16 (Arnold et al., 2005; Zsiros et al., 2015; Lieber et al., 2018).