Even with reduced T cell doses to 1 X106 (Figure 4B) and 0.5 X106 (Figure 4C) splenic T cells per animal to cause less severe GvHD, 107 IFNγ prelicensed MSCs derived from C57BL/6 animals given on days 2, 8 or days 1,3 5 post BMT did not impact GvHD (Figures 4B, C). The gene discussed is IFNG; the disease is graft versus host disease.