CD8A and type 1 diabetes mellitus: Previously, the MS- and T1D-associated CpG-sites in the IL2RA 5’UTR and promotor were shown to be methylated in a cell-specific manner and it is possible that the CpG-sites are associated with the MS-associated IL2RA SNP rs2104286 in other cell types than CD8+ T cells (13, 36).