In one of the published reports, it was found that MVs secreted by BMSCs are efficient in the treatment of acute lung injury (ALI) caused by E. coli endotoxins via transfer of keratinocyte growth factor (KGF) mRNA from the MVs to damaged lung endothelium and alveolar epithelium (Zhu et al., 2014). The gene discussed is FGF7; the disease is acute respiratory distress syndrome.