CIC and brain neoplasm: In brain tumors, Cic mutations were found in oligodendroglioma (Bettegowda et al., 2011; Yip et al., 2012), oligoastrocytoma (Sahm et al., 2012), astrocytoma (Sahm et al., 2012), glioblastoma (Bunda et al., 2019) and medulloblastoma (Lee et al., 2005).