NRAS and cancer: Mutations in well-known cancer genes located on chromosome 1p, such as NRAS (1p13.2), GADD45A (1p31.2–31.1), CDKN2C (1p32.2), RAD45(1p32) and EPB41 (1p36.2–p34), have so far only sporadically been detected26,28,34,35.