SH2B3 and coronary artery disorder: In addition, we further identified nine significant genes in PUBB (ADAMTS7, APOE, LPA, SH2B3, HNF1A, CELSR2, MYBPHL, ANGPTL4, EHBP1L1) that have been previously reported to be associated CAD by GBA (Table 1)6,23,24.