To examine whether BAK is also partially activated in ovarian cancer cell lines, BCLXL, MCL1, and BCL2 were immunoprecipitated from 13 untreated ovarian cancer cell lines (Fig. 1 and Supplementary Fig. 1), and the percentage of bound BAK was analyzed (Supplementary Fig. 2). This evidence concerns the gene BCL2L1 and ovarian carcinoma.