MYOC and proteostasis deficiencies: Inspired by the advances in other protein misfolding diseases that have been catalyzed by the availability of conformation-dependent and recombinant antibody reagents (6, 7, 8, 9, 10, 11, 40, 41, 42), we aim to ultimately develop a toolbox of new high-quality antibodies for myocilin, a relatively new addition to the list of proteins associated with misfolding diseases.