TRDMT1 and schistosomiasis: A previous study showed that S. mansoni contains conserved DNA methyltransferase 2 (DNMT2) and methyl-CpG binding proteins (MBD) [6, 7] and it is suggest that pharmacological inhibition of SmMBD2/3 and/or SmCBX biology could prove useful in the development of future schistosomiasis control strategies [8].