HIF1A and COVID-19: The factors that may be related to lower susceptibility to COVID-19 involve physiological and anatomical adaptations in the lungs, with perfusion and capacity improvements, but mainly hypoxia-inducible-factor-1α (HIF-1α) activation [5–7], which has become scientifically relevant due to its discovery behind the Nobel Prize in Physiology or Medicine in 2019 [11].