Falci et al. in Brazil demonstrated that < 50 CD4 + cells/μL, pancytopenia, miliary pattern on thorax imaging, hepatomegaly, generalized lymphadenopathy and LDH > 1000 IU/L, are factors that may aim for the prediction of Probable/Proven histoplasmosis [19]. The gene discussed is CD4; the disease is Pancytopenia.