Sherva et al. identified 42 SNPs associated with DSM-IV cannabis dependence criteria count across 27 different genes/regions including INTS7, SNORA26, RPS20P10, PI4K2B, CSMD1, PSMB7, HABP2, MEFV, CST7, APMAP, ACSS1, snoU13, TPST2, SCN9A, CTA-445C9.15, CTA-445C9.14-CTA-4, SCN9A-SCN7A, ARL2BPP5-RP11-541P9.3, RP11-755E23.3-CCDC67, SNORD11-RNU6-1014P, RP5-860P4.2-CST7, RNU6-1257P, APMAP-ACSS1, C9.15, RPS20P10-CYP26B1, PI4K2B-ZCCHC4, and CST7-APMAP. The gene discussed is APMAP; the disease is cannabis dependence.