In the previous APAC group, EPO had a significant correlation with pre-operation IOP and number of preoperative eyedrops, PDGF-AA and PDGF-BB only had a significant correlation with pre-operation IOP, while PDGF-DD had a significant correlation with sex and interval between the onset of APAC and trabeculectomy. This evidence concerns the gene EPO and aldosterone-producing adrenal cortex adenoma.