69.18%(202/292)的儿童AML患者携带融合基因,而成人AML患者中融合基因阳性率为44.77%(1746/3900),二者差异具有统计学意义(P<0.001)。此外,PML-RARα、RUNX1-RUNX1T1、MLL-AF10和MLL-AF1q阳性患者在儿童AML中占比高于成人,而累及NUP98的融合基因阳性患者均为成人。. The gene discussed is RUNX1T1; the disease is acute myeloid leukemia.