Comparing 13 cases of SET-NUP214-positive and 62 cases of SET-NUP214-negative T-ALL, the CR rates of induction chemotherapy were 92.3% and 93.5%(P=0.445), and the 4-week CR rates of induction chemotherapy were 69.2% and 72.6%, respectively(P=0.187); the differences were not statistically significant. This evidence concerns the gene NUP214 and acute lymphoblastic leukemia.