HIV-related characteristics among HIV/lipo participants and HIV/nonlipo participants differed by duration of HIV infection (24 ± 2 vs. 18 ± 3 years, P = 0.07), duration of ART (20 ± 2 vs. 11 ± 2 years, P = 0.007), duration of protease inhibitor use (16 ± 3 vs. 9 ± 2 years, P = 0.08), and CD8+ count (725 ± 115 vs. 1260 ± 164 cells/μL, P = 0.02) (all ranges show mean ± SEM). This evidence concerns the gene CD8A and HIV infectious disease.