Given that DS‐lncRNA co‐expressed with Raly mRNA, Ehmt2 mRNA, and downstream target Kcna2 mRNA in individual large, medium, and small DRG neurons as well as downstream target Oprm1 mRNA in individual medium and small DRG neurons (Figure S24a–c, Supporting Information), our results indicate that DS‐lncRNA downregulation may enhance the binding of RALY to RNP II and Ehmt2promoter, leading to a RALY/RNP II‐triggered increase in Ehmt2 mRNA/G9a in injured DRG after peripheral nerve injury. This evidence concerns the gene KCNA2 and peripheral nerve injury.