Inflammation status was also independently associated with sarcopenia in CKD subjects, not only measured by high malnutrition inflammation scores [25, 37] but also by high levels of inflammatory markers in sarcopenic groups, including high-sensitive C-reactive protein (hs-CRP) [24, 32, 35, 36, 40], interleukin-6 (IL-6) [34–36], ß2-microglobulin [35, 36], and interleukin-4 (IL-4) [24]. This evidence concerns the gene IL6 and nutritional deficiency disease.