APOE and atherosclerosis: This acceleration of atherosclerosis by BMDM–HG-exo occurred in part by an increase in the number of lesional macrophages as detected by MOMA-positive immunofluorescent staining in Apoe−/− fed a chow diet (Figures 3D and 3E) and in Apoe−/− fed a Western diet (Figure 3F) as compared to mice treated with saline or BMDM–NG-exo.