Interestingly, patients suffering from the accelerated aging disease Hutchinson Gilford Progeria Syndrome (HGPS) often die from CVDs like myocardial infarction (MI) or stroke (68) and HGPS is associated with amplified interferon responses potentially via the cGAS-STING pathway (69–71). The gene discussed is CGAS; the disease is Hutchinson-Gilford progeria syndrome.