AKT1 and pulmonary fibrosis: The upregulation of miR-193a in paraquat-induced pulmonary fibrosis leads to the downregulation of the PI3K/AKT/mTOR axis and the upregulation of its downstream autophagy-related LC3-II/LC3-I and Beclin1, which induced the autophagy of lung fibroblasts and then reduced the expression of pulmonary fibrosis marker protein α-SMA and collagen deposition (Liu et al., 2019).