In a study by Xu et al., miR-125a-3p directly targetted 3′UTR of Fyn and then lead to the inactivation of the Fyn downstream effector STAT3, which inhibited the progression of silica-induced murine pulmonary fibrosis and TGF-β1-treated fibroblast lines (Xu et al., 2019). This evidence concerns the gene TGFB1 and pulmonary fibrosis.