STAT3 and renal fibrosis: Subsequently, Bijkerk et al. suggested that miR-132 may coordinately mediate genes involved in TGF-β signaling, STAT3/ERK pathways, and cell proliferation (Foxo3/p300) related to promoting trans-differentiation and proliferation of myofibroblasts during the formation of renal fibrosis (Bijkerk et al., 2016).