Some studies reported that miRNAs, including miR-18a-5p, miR-153, and miR-1344, play anti-pulmonary fibrosis effects for targeting TGF-β receptors to inhibit downstream SMAD-2/3 expression (Liang et al., 2015; Stolzenburg et al., 2016; Zhang et al., 2017). The gene discussed is SMAD2; the disease is pulmonary fibrosis.