In addition, dysregulation of other pathways, such as regulation of apoptosis (Jordan, 2015; Ahmed et al., 2019), DNA damage checkpoints (Lord and Ashworth, 2012; del Rincón et al., 2014), and P53 signaling pathway (Silwal-Pandit et al., 2017), were also involved in cancer cell growth, proliferation, invasion, and metastasis and played crucial roles in BC cells. The gene discussed is TP53; the disease is cancer.