Currently, the conventional clinicopathologic indicators, including tumor size, lymph node metastasis, TNM stage, and cellular biomarkers (ER, PR, HER-2 status and Ki-67 index) of tumor biopsy, are still the gold standard for the risk stratification and subsequent formulating of therapeutic scheme. The gene discussed is PGR; the disease is metastatic malignant neoplasm in the lymph nodes.