RECQL and neoplasm: RECQ1 has recently been reported to confer specific oncogene effects, including cell cycle progression in the S-phase, to tumors, and systemic depletion of RECQ1 has been shown to prevent tumor growth in murine models (Futami et al., 2008; Arai et al., 2011; Mendoza-Maldonado et al., 2011), but a direct role for RECQ1 in DNA replication and cellular processes has not been identified.