Similar results were found that elevated BST2 level, HOXC6, and TNNT1 level are correlated with poor prognosis in colon cancer patients, while TNNT1 protein may be mediated through the process of epithelial–mesenchymal transition (Chiang et al., 2015; Hao et al., 2020; Yuan et al., 2020). Here, HOXC6 is linked to malignant colon neoplasm.