CCR5 and Chagas cardiomyopathy: Moreover, CCR-mediated cell migration has been shown to be crucial for acute and chronic experimental Chagas cardiomyopathy, as CCL5/CCR5- and CCL3-driven cell migration has been found crucial for inflammatory Th1-cell invasion of tissue, cardiac injury, and electrical abnormalities, such as prolonged QTc (Batista et al., 2018; Gibaldi et al., 2020).