H3K9me2/3 was significantly enriched at the promoter regions of both Atg5 (Figure 3A; P ≤ 0.01) and Atg7 (Figure 3B;P ≤ 0.001) in response to MtbPrt bacterial infection, while no such enrichment was observed in uninfected and MsmpSMT3-infected cells. The gene discussed is ATG5; the disease is bacterial infectious disease.