NFKB1 and ovarian carcinoma: In this study, drug-resistant ovarian cancer cells (A2780/DDP) were used to investigate whether TPL inhibited the invasion and migration of drug-resistant ovarian cancer by inhibiting the polarization of M2 TAMs through the PI3K/AKT/NF-κB signaling pathway, and to explore the relationship between TPL and the intestinal microbiota.