We previously showed that triptolide (TPL), one of the primary active ingredients of Tripterygium wilfordii, which is a Traditional Chinese Medicine that has been reported to be therapeutically efficacious in rheumatoid arthritis, inhibited the growth, invasion, and migratory capability of drug-resistant ovarian cancer cells (30) and reversed the resistance of ovarian cancer cells to cisplatin by inhibiting the phosphorylation of AKT (31). Here, AKT1 is linked to ovarian cancer.