We analyzed the clusters of overexpressed and repressed genes common to both “MK-2206” and “FOXM1-KD” genesets looking for genes potentially associated with AML drug sensitivity and detected increase in the expression of multiple genes belonging to HOXA family (HOXA1, HOXA3, HOXA5, HOXA6, HOXA7, HOXA11, HOXA13) (Figure 2D). This evidence concerns the gene HOXA3 and acute myeloid leukemia.