HOXA1 and acute myeloid leukemia: We analyzed the clusters of overexpressed and repressed genes common to both “MK-2206” and “FOXM1-KD” genesets looking for genes potentially associated with AML drug sensitivity and detected increase in the expression of multiple genes belonging to HOXA family (HOXA1, HOXA3, HOXA5, HOXA6, HOXA7, HOXA11, HOXA13) (Figure 2D).