PRSS8 and breast carcinoma: We further analyzed the prognostic significance of the hub genes in breast cancer patients using Kaplan–Meier plotter and found that the upregulated expressions of CLDN7, CLDN3, EPCAM, KRT8, KRT18, RAB25, and KRT19 were significantly correlated with DMFS in breast cancer (Figures 9C–I), but PRSS8, PKP3, and CLDN4 expression was not (Figures 9J–L).