The results showed that higher expression of SPINT1 was correlated with poorer OS (HR = 1.53, 95% CI = 1.22–1.92, P = 0.00019), RFS (HR = 1.21, 95% CI = 1.07–1.37, P = 0.002), and DMFS (HR = 1.42, 95% CI = 1.15–1.74, P = 0.00094) in breast cancer patients (Figures 4A–C). This evidence concerns the gene SPINT1 and breast cancer.