GSK3B and colorectal carcinoma: On the other hand, some monomers derived from traditional Chinese herbs such as Luteolin, C. brachycephalum, pterisolic acid G (PAG), wogonin, nerigoside (NG) and isobavachalcone (IBC), exhibit anticancer functions by affecting the phosphorylation state of GSK-3β and ß-catenin in CRC.