IL6 and Alzheimer disease: Several interleukins, including IL-2, IL-6, and IL-1β, tumor necrosis factor (TNF-α), and anti-inflammatory transforming growth factorβ1 (TGFβ1) were found in enhanced levels in AD subjects [25, 47], and the explication of the postmortem samples manifested the higher amounts of IL-1β, interferon-γ (IFN-γ), TNF-α, and NOS and the generation of free radicals.