In addition, high-throughput affinity plasma proteomic profiling of VTE patients showed that PDGF-β was an independent risk factor of thrombosis-related disorders63, and HIF1α and CREB1 were enriched in growth factor related-GO BP terms with VEGF as the common target in murine macrophages22,64. The gene discussed is HIF1A; the disease is Venous thrombosis.