In the univariate analysis, the following 12 factors had a significant impact on OS and RFS: age at surgery (< 65 versus ≥ 65), tumor location, tumor size (< 5 versus ≥ 5 cm), histology, N stage, lymphovascular invasion, lymph node retrieval (> 12 versus ≤ 12), surgical procedure, CEA level, CA19-9 level, postoperative complications and postoperative adjuvant chemotherapy (Table 2). Here, CEACAM5 is linked to neoplasm.