ICAM1 and neoplasm: Using flow cytometry analyses and IHC staining, we first confirmed the highly enriched ICAM1 expression (17–99%) in the lung metastases of three TNBC PDX models (TN1, TN2, and TN3) compared to that of primary tumor cells (0.5–36%, P < 0.05 or 0.01) (Fig. 1c–e and Supplementary Fig. 1d).