Physcion 8-O-beta-glucopyranoside (PG) exerted an anti-tumor role in GC by downregulating inhibitory effect of miR-103a-3p on glutaminase 2 (GLS2) expression, and the upregulating ROS level, intracellular Fe(2+) level, and malondialdehyde (MDA) generation [110]. This evidence concerns the gene GLS2 and gastric cancer.