FGFR3 and central nervous system cancer: In glioma, FGFR3 is regulated negatively by miR-99a, while in cervical cancer, FGFR3-TACC3, which has lost the FGFR3 3′ UTR region, has been proven to be a carcinogenic fusion that activates the MAPK pathway by increasing its FGFR3 signal [79].