We showed that auranofin increased disulfiram-induced MLL1 degradation in pediatric glioma cells when used at a concentration of 0.5 μM (Fig. 2A–E, conditions 6 and 7), while auranofin alone had no effect on MLL1 protein levels (Fig. 2A–E, condition 5). Here, KMT2A is linked to glioma.