By immunohistochemical detection of MYH11, TNFRSF14, and Ki67 expression in harvested xenograft tumors, we observed a significant increase in MYH11 expression and a significant decrease in Ki67 and TNFRSF14 expression in tumor tissues from the mice injected with cells overexpressing MYH11 (Fig. 8C). The gene discussed is TNFRSF14; the disease is neoplasm.