FGF21 and Dravet syndrome: In addition, the mean of log10 FGF‐21 level was significantly higher in DS patients with valproate treatment (Mean ± SEM: 2.741 ± 0.1842; n = 15) comparing with those without valproate treatment (Mean ± SEM: 1.716 ± 0.4125; n = 7) by unpaired t‐test (two‐tailed P value = .015) (Figure 2B).