Macronutrient content of food is a key factor affecting gastric emptying andfoods with a high fat or protein load are known to delay gastric emptying bycausing the release of peptides such as glucagon like peptide-1 (GLP-1), gastricinhibitory polypeptide (GIP) and cholecystokinin (CCK).37 Resultant delayed hyperglycemia and insulin resistance38 leads to glucose patterns similar to those typically observed in peoplewith gastroparesis. This evidence concerns the gene GIP and Hyperglycemia.