DPP4 and colorectal carcinoma: We supplemented the ATAC‐seq open chromatin maps with high‐resolution annotation of the H3K27ac histone activation marker using Mint‐ChIP, a technique that requires far fewer cells than conventional ChIP‐seq and is hence more compatible with the in vivo metastasis model.[25] Consistent with chromatin accessibility results, Mint‐ChIP showed that the DPP4 promoter and three enhancers harbored more H3K27ac histone activation markers in CRC liver metastases than in primary CRC tumors (Figure 2F and Figure S2D, Supporting Information).