Previous reports showed that inhibition of DPP4 induced breast and prostate cancer metastasis via the CXCL12/CXCR4/mTOR axis and epithelial‐to‐mesenchymal transition (EMT).[48, 49] This highlights the importance of context, which includes cancer type, stage, and microenvironment. Here, CXCL12 is linked to Familial prostate cancer.