SUB1 and atherosclerosis: The consumption of a Western diet (i.e., high cholesterol and saturated fatty acid content) contributes to enhanced circulating cholesterol levels, oxLDL‐induced macrophage activation, and pathogenic foam cell differentiation.[21] To analyze the role of Sub1‐deficient macrophages in Western diet‐induced atherosclerosis in vivo, we examined the effect of transplanting transgenic bone marrow into a Western diet‐fed Ldlr−/− murine model of atherosclerosis.