TSC2 and cancer: In addition, analyzing data from The Cancer Genome Atlas (Cancer Genome Atlas Network, 2012), the expression profiles of HRH1 and TSC2 were found to be negatively correlated (PCC = −0.15, P = 2 × 10‐6) and, conversely, HRH1 expression was found to be positively correlated with the canonical lung‐metastasis signature (Minn et al, 2005) and mTOR pathway (Appendix Fig S4B).