In case-only analyses, the association between smoking status and CRC risk was statistically significantly stronger for BRAF-mut, KRAS-wt, MSI-H, and CIMP+ CRC subtypes among current smokers only but not among former smokers, after Bonferroni correction (Pdifference < 6.3 x 10-3; Table 2). Here, KRAS is linked to colorectal carcinoma.