PTEN and myelodysplastic syndrome: Ozdogan et al. relate an interesting fact: in MDS, not onlymiRNA expression levels are changed, but also the expression of theDICER1 gene, a key participant in the canonical miRNAprocessing pathway, is decreased [71].In particular, Jang et al. conclude that increased expressionlevels of miRNA-205-5p promote MDS by suppressing PTEN and,thus, acting as an oncogene in hematopoietic cells.