This is illustrated by the higherlevels of C-reactive protein (CRP) in female patients with chronicinflammatory diseases.69 In line with this, CRP levels were positively correlated with therelative risk of CHD, independent of traditional cardiovascular risk factors.70 The contribution of sex hormones in development of ASCVD in IBDpatients remains elusive. This evidence concerns the gene CRP and coronary artery disorder.